American Journal of Clinical Medicine Research. 2014, 2(4), 84-86
DOI: 10.12691/AJCMR-2-4-5
Review Article

Serum Creatinine in Normal Sudanese Athlets and Soldiers

Nagah A. A. Mohamed1, , Jumana M. ELhafiz2 and Faroug B.M.Ahmed3

1Sudan University of science and technology

2Sudan Ministry of health

3Department of biochemistry, Faculty of Science and Technology, Shendi University

Pub. Date: September 10, 2014

Cite this paper

Nagah A. A. Mohamed, Jumana M. ELhafiz and Faroug B.M.Ahmed. Serum Creatinine in Normal Sudanese Athlets and Soldiers. American Journal of Clinical Medicine Research. 2014; 2(4):84-86. doi: 10.12691/AJCMR-2-4-5

Abstract

Plasma levels of creatinine are related to the relative muscles mass, the rate of creatine turnover and the renal function. It has been accepted for years that the plasma level of creatinine is relatively un affected by the diet. However, some reports have indicated that the protein content of the diet may be indeed affect the plasma level of creatinine if it affects the individuals muscles mass. This a primary study that aims to detect rough estimation of serum creatinine in normal Sudanese athletes and soldiers. In addition to detect weather creatinine level is associated by gender, age, daily working hours or occupation of study population. Hundred (49 soldiers: 51 athletes) normal individuals from Khartoum state invited to take a role in this study (75 male: 25 female) their age was between 14-44 years. At P ≤ 0.05 this study showed no significant differences (P 0.772) in creatinine concentration with mean ± SD (1.07 ± 0.11, 1.12 ± 0.17 mg/dl) for soldiers and athletes respectively. There was no signifigant difference in creatinine concentration either between both sexes male: female (1.1 ± 0.16: 1.1 ± 0.12), or between different occupations soldiers: athletes (1.07 ± 0.11: 1.12 ± 0.17). But there was significant difference (Chi 0.027) in creatinine concentration (0.5, 1.0, 1.5) for (14-24, 25-34, 35-44) age groups respectively. Serum creatinine was not associated with daily working hours (ANOVA 0.18) with creatinine values (1.16, 1.01, 1.12, 1.13, 0.8) for weekly working hours (≤ 20, 21- 40, 41- 60, 61 – 80, 81-100). Serum creatinine is not much different depending on the gender, individual occupation or daily working hours, weather they were soldiers or athletes, but it is influenced by age progress. Sudanese soldiers and Athletes creatinine level fell within the normal international range. Research with large data collection is recommended for establishment and localization normal range of biochemical parameters for sport medicine in Sudan.

Keywords

soldiers athletes, serum creatinine, muscles

Copyright

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References

[1]  Allen P.J. (2012).Creatine metabolism and psychiatric disorders: Dose creatine supplementation have therapeutic value?. Neurosci Biobehav Re 36 (5): 1442-62.
 
[2]  Banfi G., Colombin A., Lombadig G. and Lubkowska A. (2012). Metabolic markers in sports medicine. Adv Clin Chem, 2012; 56: 1-54.
 
[3]  Clark J. (2000). Laboratory medicine and pathology. Laboratory Evaluation of Renal Function: Creatinine Clearance as an Estimate of GFR –www.easybib search. March, 9, 2000.
 
[4]  Fabbro M.,. and Lippi G. (2009). Serum creatinine concentration and creatinine-based estimation of glomerular filtration rate in athletes. Sport Med.; 39(4):331-7.
 
[5]  Ganon,W.F.(1999).Review of medical physiology, 19th edn. Appleton and Lange, San Francisco, California.
 
[6]  Gross J, L., de Azevedo M.J., Silveiro S.P., Canani L.H., Caramori M.L. and Zelmanovitz T. (2005). "Diabetic nephropathy: diagnosis, prevention, and treatment". Diabetes Care 28 (1): 164-76.
 
[7]  Murray K.R,Granner K.D. and Rodwell W.V. (2007). Harpper’s illustrated biochemistry, 27th edition, Mc Graw Hill Lange, international edition, p: 274.
 
[8]  Roth E. (2012). Creatinine Blood Test. Health line. August 20(5) 13-20.
 
[9]  Taylor E. H. (1989). Clinical Chemistry. New York: John Wiley and Sons. pp. 4, 58-62.
 
[10]  Tonomura Y, Morikawa Y, Takagi S, Torii M, Matsubara M. (2013) Underestimation of urinary biomarker-to-creatinine ratio resulting from age-related gain in muscle mass in rats. Toxicology Jan 7; 303: 169-76.
 
[11]  Vasudervan DM., Sreekumari and Vaidyanathan K. (2011). Textbook of biochemistry for medical students, 6th, Jaypee brothers medical publishers (p) LTD. P: 320-21.